Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.36 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.35 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7446703 | 1.00 | KDR (0.36) | KDREIF2AK3EIF2AK1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL7213548 | 0.91 | HRH4 (0.34) | HRH4HRH3F10DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL7453206 | 0.91 | HRH4 (0.34) | HRH4HRH3F10DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL7446696 | 0.89 | KDR (0.35) | KDREIF2AK3EIF2AK1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL7219132 | 0.89 | KDR (0.35) | KDREIF2AK3EIF2AK1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL7219407 | 0.89 | KDR (0.35) | KDREIF2AK3EIF2AK1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL7457544 | 0.85 | F10 (0.35) | HRH4HRH3F10DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL7215793 | 0.85 | F10 (0.35) | HRH4HRH3F10DPP4DPP7 | |
| SCHEMBL7456514 | 0.80 | F10 (0.38) | F10F2PLGPLATPROC | |
| SCHEMBL7213494 | 0.80 | F10 (0.38) | F10F2PLGPLATPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |