SCHEMBL7219217

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7213515	1.00	HTR1A (0.40)	HTR1ADRD2HTR2AHRH3TDP1
	SCHEMBL7214344	0.88	POLB (0.42)	TDP1POLBMAPTALDH1A1MEN1
	SCHEMBL7215933	0.88	POLB (0.42)	TDP1POLBMAPTALDH1A1MEN1
	SCHEMBL7453627	0.84	HRH3 (0.57)	HTR2AHRH3KCNJ1KCNH2
	SCHEMBL7453632	0.84	HRH3 (0.57)	HTR2AHRH3KCNJ1KCNH2
	Hydrochloric Acid SCHEMBL7213524	0.83	HRH3 (0.56)	HRH3KCNJ1KCNH2
	Hydrochloric Acid SCHEMBL7213525	0.83	HRH3 (0.56)	HRH3KCNJ1KCNH2
	SCHEMBL16293628	0.78	HRH3 (0.64)	HTR1ADRD2HTR2AHRH3TDP1
	Ammonia Solution, Strong SCHEMBL28185355	0.78	HRH3 (0.64)	HTR1ADRD2HTR2AHRH3TDP1
	SCHEMBL7381397	0.78	KDM4E (0.42)	HTR1ADRD2HTR2AHRH3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.