Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.37 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PLG | P00747 | 3/20 | 0.36 |
| ▸ | PROC | P04070 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214254 | 0.86 | TSHR (0.32) | PDE7BALDH1A1MAPK1KDM4ETSHR | |
| SCHEMBL7213898 | 0.86 | F10 (0.39) | P2RX7F10F2PLGPROC | |
| Hydrochloric Acid SCHEMBL7213582 | 0.85 | F10 (0.38) | P2RX7F10F2PLGPROC | |
| Hydrochloric Acid SCHEMBL7213579 | 0.85 | F10 (0.38) | P2RX7F10F2PLGPROC | |
| Trifluoroacetic Acid SCHEMBL7213074 | 0.82 | GPR6 (0.35) | F10F2 | |
| SCHEMBL7213893 | 0.82 | P2RX7 (0.40) | P2RX7F10F2PLGPROC | |
| SCHEMBL7220633 | 0.81 | F10 (0.42) | P2RX7F10F2PLGPROC | |
| SCHEMBL9461582 | 0.74 | HDAC1 (0.45) | ALDH1A1HPGDTSHR | |
| SCHEMBL7214087 | 0.73 | ACACB (0.42) | P2RX7F10F2PLGPROC | |
| SCHEMBL7541709 | 0.72 | F10 (0.46) | F10F2PLGPROCPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |