Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886677 | 0.83 | KDM4E (0.59) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL9330597 | 0.80 | KDM4E (0.43) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL2886094 | 0.77 | KDM4E (0.53) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL20971905 | 0.77 | KDM4E (0.49) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL18987369 | 0.76 | KDM4E (0.51) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL7223413 | 0.72 | KDM4E (0.47) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL9754434 | 0.71 | IL2 (0.46) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL31048531 | 0.69 | KDM4E (0.53) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL7223905 | 0.69 | KDM4E (0.53) | KDM4EHTTLMNAMAPTIL2 | |
| SCHEMBL10746575 | 0.68 | KDM4E (0.51) | KDM4EHTTLMNAMAPTIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | disclosed |
| US-6410558-B1 | USING INDOLE OR QUINOLINE COMPOUND | MONSANTO TECHNOLOGY LLC | 2002-06-25 | — | — | US | disclosed |
| US-20010046975-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY | 2001-11-29 | — | — | US | disclosed |
| US-6252078-B1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6248894-B1 | SUBSTITUTED PYRROLES | MONSANTO COMPANY | 2001-06-19 | — | — | US | disclosed |
| EP-1088481-A2 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 2001-04-04 | — | — | EP | disclosed |
| US-6166057-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| US-6133252-A | THIOPHENE AND N-BONDED HETEROCYCLIC COMPOUND CHOSEN FROM THE GROUP CONSISTING OF MORPHOLINE, PIPERAZINE, PIPERIDINE, AND PYRROLIDINE, EACH OPTIONALLY SUBSTITUTED WITH C1-C6 ALKYL GROUPS | MONSANTO COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-6028101-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 2000-02-22 | — | — | US | disclosed |
| US-RE36562-E | CARBOXAMIDE-SUBSTITUTED THIOPHENES | MONSANTO COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| US-5998466-A | PREPLANTING | MONSANTO COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5849723-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5498630-A | SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |
| WO-1993007751-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538231-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010046975-A1 | Fungicides for the control of take-all disease of plants | CNPY3, NAT1, CBR3 | KDM4E 2327/4885HTT 110/4885LMNA 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.