Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.43 |
| ▸ | F10 | P00742 | 10/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186033 | 0.85 | F10 (0.60) | CHEK2F10 | |
| SCHEMBL6190594 | 0.80 | F10 (0.60) | CHEK2F10 | |
| SCHEMBL6189276 | 0.77 | F10 (0.71) | F10 | |
| SCHEMBL6189265 | 0.77 | F10 (0.52) | CHEK2F10 | |
| SCHEMBL6186020 | 0.75 | F10 (0.46) | CHEK2F10GPR119 | |
| SCHEMBL6190591 | 0.75 | CHEK2 (0.48) | CHEK2F10 | |
| SCHEMBL6189272 | 0.74 | F10 (0.57) | CHEK2F10 | |
| SCHEMBL6188232 | 0.74 | F10 (0.60) | CHEK2F10 | |
| SCHEMBL6192371 | 0.73 | GPR119 (0.48) | CHEK2F10GPR119 | |
| SCHEMBL6192378 | 0.72 | F10 (0.55) | CHEK2F10GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562828-B1 | Novel amidine compound having a blood coagulation factor Xa inhibitory activity | JAPAN TOBACCO INC. (JP) | 2003-05-13 | — | — | US | disclosed |