Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21705943 | 0.93 | TSHR (0.53) | TSHRHSD17B10L3MBTL1TDP1HPGD | |
| SCHEMBL26169758 | 0.93 | TSHR (0.53) | TSHRHSD17B10L3MBTL1TDP1HPGD | |
| SCHEMBL7219748 | 0.89 | PDCD1 (0.38) | TSHRHSD17B10CHRNB2CHRNA4RAF1 | |
| SCHEMBL7213725 | 0.81 | CYP2A6 (0.48) | CHRNB2CHRNA4RAF1GRIN1GRIN2B | |
| SCHEMBL10807925 | 0.80 | TDP1 (0.50) | TSHRCHRNB2CHRNA4L3MBTL1TDP1 | |
| SCHEMBL23783636 | 0.78 | CHRNA7 (0.41) | CHRNB2CHRNA4RAF1HTTGRIN1 | |
| SCHEMBL27209742 | 0.78 | HRH3 (0.37) | HSD17B10RAF1HPGDMAPK1GRIN1 | |
| SCHEMBL18728443 | 0.78 | CYP11B1 (0.36) | HSD17B10CHRNB2CHRNA4RAF1HPGD | |
| SCHEMBL3508498 | 0.77 | GRIN1 (0.35) | CHRNB2CHRNA4RAF1GRIN1GRIN2B | |
| SCHEMBL24615861 | 0.77 | GRM5 (0.38) | RAF1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |
| CN-1043760-C | \"Pyridinecarboximidamide compounds and the use thereof\ | KIRN BEER KABUSHIKI KAISHA (JP) | 1999-06-23 | — | — | CN | disclosed |
| CN-1077949-A | Pyridine carboxy imido acid amide compound and application thereof | KIRIN BREWERY (JP) | 1993-11-03 | — | — | CN | disclosed |