Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 14/20 | 0.42 |
| ▸ | CTSB | P07858 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6111527 | 0.88 | CTSS (0.50) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6111534 | 0.88 | CTSS (0.50) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6107557 | 0.86 | CTSS (0.64) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5364142 | 0.85 | CTSS (0.63) | CTSSCTSL | |
| SCHEMBL5364140 | 0.85 | CTSS (0.63) | CTSSCTSL | |
| SCHEMBL6112353 | 0.85 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6112347 | 0.85 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL14383664 | 0.85 | CTSS (0.47) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6107436 | 0.85 | CTSS (0.44) | CTSSCTSLCTSKCTSB | |
| SCHEMBL7070928 | 0.84 | CTSS (0.53) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525052-B2 | Treating autoimmune diseases, Alzheimer's disease, atherosclerosis, osteoporosis, and asthma | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-02-25 | — | — | US | claimed |