⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406741 | 1.00 | — | — | |
| SCHEMBL722018 | 1.00 | — | — | |
| SCHEMBL7520988 | 0.83 | — | — | |
| SCHEMBL7520985 | 0.83 | — | — | |
| SCHEMBL7520661 | 0.81 | — | — | |
| SCHEMBL7520666 | 0.81 | — | — | |
| SCHEMBL17744090 | 0.79 | FAAH (0.48) | — | |
| SCHEMBL17743982 | 0.79 | FAAH (0.48) | — | |
| SCHEMBL9482930 | 0.79 | FAAH (0.48) | — | |
| SCHEMBL17743953 | 0.79 | FAAH (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161651-A1 | QUINAZOLINE-DERIVED HCK INHIBITORS FOR USE IN THE TREATMENT OF MYD88 MUTATED DISEASES | Dana-Farber Cancer Institute, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-4027993-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| WO-2021050700-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| EP-3787612-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2021-03-10 | — | — | EP | disclosed |
| EP-3606528-A1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | The Broad Institute, Inc. (US) | 2020-02-12 | — | — | EP | disclosed |
| WO-2018187630-A1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2018-10-11 | — | — | WO | disclosed |
| WO-2018053373-A1 | USES OF SATL-INDUCIBLE KINASE (SIK) INHIBITORS FOR TREATING OSTEOPOROSIS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-03-22 | — | — | WO | disclosed |
| EP-3214935-A1 | EZH2 INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2017-09-13 | — | — | EP | disclosed |
| CN-104854155-B | Photocurable composition | 株式会社ADEKA | 2017-08-15 | — | — | CN | disclosed |
| WO-2016073956-A1 | EZH2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
| EP-0885875-A1 | VINYLENE COMPOUNDS AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0872484-A1 | ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0504812-B1 | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL CO (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5302619-A | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0355552-B1 | Alkoxymethyl- and alkenyloxymethyl-cyclohexanes | HOFFMANN LA ROCHE (CH) | 1994-02-23 | — | — | EP | disclosed |
| US-5262441-A | APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0504812-A2 | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-5102578-A | Electrooptics | HOFFMANN-LA ROCHE INC. (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0355552-A2 | Alkoxymethyl- and alkenyloxymethyl-cyclohexanes | F. HOFFMANN-LA ROCHE AG (CH) | 1990-02-28 | — | — | EP | disclosed |
| US-4451285-A | Herbicidal 2-haloacetanilides | MONSANTO COMPANY (US) | 1984-05-29 | — | — | US | disclosed |