SCHEMBL7220271

SCHEMBL7220271

CCCCCCCCCCCCN(C)C(=O)Cn1cc(Cc2cnc(=O)n(CC(=O)O)c2)c(=O)nc1SCc1ccc(F)cc1.[Na]

nearest known ligand 0.99

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 20/20 0.99

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6950524 0.99 PLA2G7 (1.00) PLA2G7
SCHEMBL6946577 0.99 PLA2G7 (1.00) PLA2G7
SCHEMBL6949557 0.92 PLA2G7 (0.86) PLA2G7
SCHEMBL6946430 0.92 PLA2G7 (0.86) PLA2G7
SCHEMBL6952858 0.91 PLA2G7 (0.85) PLA2G7
SCHEMBL6954063 0.91 PLA2G7 (0.85) PLA2G7
SCHEMBL6947767 0.90 PLA2G7 (0.84) PLA2G7
SCHEMBL6949724 0.90 PLA2G7 (0.84) PLA2G7
SCHEMBL6947946 0.88 PLA2G7 (0.79) PLA2G7
SCHEMBL6946565 0.88 PLA2G7 (0.79) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6559155-B1 Phospholipase A2 enzyme Lipoprotein Associated Phospholipase A2 inhibitors SMITHKLINE BEECHAM P.L.C. (GB) 2003-05-06 US claimed