Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119390 | 0.92 | ESR1 (0.39) | ESR1 | |
| SCHEMBL7221248 | 0.91 | ESR1 (0.52) | ESR1 | |
| SCHEMBL7225027 | 0.91 | ESR1 (0.52) | ESR1 | |
| SCHEMBL7219515 | 0.91 | ESR1 (0.52) | ESR1 | |
| SCHEMBL7221154 | 0.91 | ESR1 (0.52) | ESR1 | |
| SCHEMBL7227372 | 0.90 | ESR1 (0.38) | ESR1 | |
| SCHEMBL7220419 | 0.89 | ESR1 (0.44) | ESR1 | |
| SCHEMBL7218944 | 0.88 | ESR1 (0.54) | ESR1 | |
| SCHEMBL7219789 | 0.88 | ESR1 (0.54) | ESR1 | |
| SCHEMBL7225982 | 0.88 | ESR1 (0.54) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552069-B1 | Having anti-estrogenic activity; for use in therapy | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-1241166-A1 | 3-METHYL-CHROMAN AND -THIOCHROMAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |