Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122203 | 0.93 | ESR1 (0.33) | ESR1 | |
| SCHEMBL7220319 | 0.90 | ESR1 (0.43) | ESR1 | |
| SCHEMBL7087556 | 0.86 | ESR1 (0.33) | ESR1 | |
| SCHEMBL6940319 | 0.86 | ESR1 (0.33) | ESR1 | |
| SCHEMBL5856061 | 0.85 | ESR1 (0.40) | ESR1 | |
| SCHEMBL5854915 | 0.85 | ESR1 (0.40) | ESR1 | |
| SCHEMBL7120032 | 0.83 | — | — | |
| SCHEMBL7120034 | 0.83 | — | — | |
| SCHEMBL7119390 | 0.83 | ESR1 (0.39) | ESR1 | |
| SCHEMBL7237531 | 0.83 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552069-B1 | Having anti-estrogenic activity; for use in therapy | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-1241166-A1 | 3-METHYL-CHROMAN AND -THIOCHROMAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |