Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897608 | 0.81 | CYP19A1 (0.43) | CA1CA2CA12CA7CA9 | |
| SCHEMBL20975456 | 0.80 | CA1 (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL3388914 | 0.80 | CA12 (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL3238461 | 0.79 | CA1 (0.59) | CA1CA2CA12CA7CA9 | |
| SCHEMBL3239130 | 0.77 | CA12 (0.54) | CA1CA2CA12CA7CA9 | |
| Ethane SCHEMBL27592770 | 0.77 | CA1 (0.59) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9797761 | 0.77 | ERN1 (0.56) | CA1CA2ERN1MEN1KMT2A | |
| SCHEMBL3906154 | 0.77 | ERN1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL2994301 | 0.75 | ERN1 (0.61) | CA1CA2ERN1MEN1KMT2A | |
| SCHEMBL29956391 | 0.75 | ERN1 (0.61) | CA1CA2ERN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576766-B1 | Competitive binding of phosphotyrosine-containing protein; veterinary medicine | ARIAD PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |