SCHEMBL3906154

SCHEMBL3906154

O=Cc1c(O)ccc2c(C(=O)O)c(O)ccc12

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 16/20 0.50
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28321998 0.83 ERN1 (0.61) ERN1
SCHEMBL31236213 0.83 ERN1 (0.61) ERN1
SCHEMBL3238461 0.83 CA1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL7828026 0.77 ERN1 (0.51) ERN1CA12CA1CA2CA7
SCHEMBL7220541 0.77 CA1 (0.48) ERN1CA12CA1CA2CA7
SCHEMBL17081341 0.74 KMT2A (0.52) ERN1CA12CA1CA2CA7
SCHEMBL11413711 0.73 CYP3A4 (0.56) ERN1CA12CA1CA2CA7
SCHEMBL14641012 0.72 LDHA (0.49) CA12CA1CA2CA7CA9
SCHEMBL3388914 0.72 CA12 (0.64) CA12CA1CA2CA7CA9
SCHEMBL9353819 0.72 ERN1 (0.60) ERN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2018844-A2 Agent for dying fibres which contain keratin comprising derivatives of naphthaldehyde in combination with CH acidic compounds Henkel AG & Co. KGaA (DE) 2009-01-28 EP claimed
EP-2018844-A2 Agent for dying fibres which contain keratin comprising derivatives of naphthaldehyde in combination with CH acidic compounds Henkel AG & Co. KGaA (DE) 2009-01-28 EP disclosed