Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3866279 | 0.82 | BCHE (0.43) | LMNAHTTNPSR1GAAMEN1 | |
| SCHEMBL4330519 | 0.82 | KMT2A (0.43) | LMNAHTTNPSR1MAPK1MEN1 | |
| SCHEMBL5350633 | 0.80 | PDPK1 (0.45) | — | |
| SCHEMBL5354727 | 0.79 | PDPK1 (0.44) | — | |
| SCHEMBL4756322 | 0.74 | NPC1 (0.44) | LMNAHTTGAAMEN1KMT2A | |
| SCHEMBL3871840 | 0.72 | POLB (0.53) | LMNAPOLBALDH1A1MAPT | |
| SCHEMBL27365676 | 0.71 | APAF1 (0.47) | LMNAMAPK1GAAKMT2APOLB | |
| SCHEMBL9602123 | 0.71 | SMN1; SMN2 (0.50) | LMNAHTTNPSR1MAPK1GAA | |
| SCHEMBL5617140 | 0.70 | POLB (0.51) | LMNAKMT2APOLBALDH1A1MAPT | |
| SCHEMBL5344472 | 0.69 | HDAC3 (0.48) | LMNAHTTPOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664265-B2 | Amido ether substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-16 | — | — | US | disclosed |