Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343465 | 0.80 | — | — | |
| SCHEMBL2482436 | 0.79 | MAPT (0.36) | ALDH1A1MAPT | |
| SCHEMBL10959047 | 0.79 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2ACHEKDM4EHSD17B10 | |
| SCHEMBL2484037 | 0.76 | MAPT (0.34) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2480155 | 0.72 | MAPT (0.32) | MAPT | |
| SCHEMBL15531026 | 0.70 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTACHEKDM4E | |
| SCHEMBL36573 | 0.67 | MAPT (0.39) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5077735 | 0.67 | MAPT (0.39) | ALDH1A1MAPTKDM4E | |
| SCHEMBL65393 | 0.67 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTACHEKDM4E | |
| SCHEMBL5792071 | 0.67 | MAPT (0.39) | ALDH1A1SMN1; SMN2MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545153-B1 | Anticholesterol agents; antilipemic agents | WARNER-LAMBERT COMPANY | 2003-04-08 | — | — | US | disclosed |