Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL16289663 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL4257733 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL4335281 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL2411393 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL3092973 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL466711 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL18140350 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL18140847 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL722452 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB | |
| Glycerin SCHEMBL10277135 | 1.00 | USP2 (0.77) | USP2HTTMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12090205-B2 | Poloxamer compositions with reduced sol-gel transition temperatures and methods of reducing the sol-gel transition temperature of poloxamer compositions | ROCHAL TECHNOLOGIES LLC (US) | 2024-09-17 | — | — | US | claimed |
| CN-117813075-A | Preservative for cosmetic and pharmaceutical compositions | 赛成公司 | 2024-04-02 | — | — | CN | claimed |
| EP-4051239-A1 | POLOXAMER COMPOSITIONS WITH REDUCED SOL-GEL TRANSITION TEMPERATURES AND METHODS OF REDUCING THE SOL-GEL TRANSITION TEMPERATURE OF POLOXAMER COMPOSITIONS | Rochal Technologies LLC (US) | 2022-09-07 | — | — | EP | claimed |
| CN-114929200-A | Method for lowering sol-gel transition temperature | 罗查尔科技有限责任公司 | 2022-08-19 | — | — | CN | claimed |
| WO-2021086698-A1 | METHODS FOR REDUCING THE TEMPERATURE OF SOL-GEL TRANSITIONS | ROCHAL INDUSTRIES, LLC (US) | 2021-05-06 | — | — | WO | claimed |
| US-20210121575-A1 | Poloxamer Compositions With Reduced Sol-Gel Transition Temperatures and Methods of Reducing the Sol-Gel Transition Temperature of Poloxamer Compositions | ROCHAL INDUSTRIES, LLC (US) | 2021-04-29 | — | — | US | claimed |
| CN-107432895-A | A kind of external plaster for expel endogenous wind to relieve convulsion | 杭州仁德医药有限公司 | 2017-12-05 | — | — | CN | claimed |
| US-20090130029-A1 | GLYCEROL ETHERS VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOAMIX LTD. (IL) | 2009-05-21 | — | — | US | claimed |
| US-12090205-B2 | Poloxamer compositions with reduced sol-gel transition temperatures and methods of reducing the sol-gel transition temperature of poloxamer compositions | ROCHAL TECHNOLOGIES LLC (US) | 2024-09-17 | — | — | US | disclosed |
| CN-117580913-A | Composition containing polyether-polysiloxane block copolymer with improved foam enhancement, use and manufacturing method thereof | 陶氏东丽株式会社 | 2024-02-20 | — | — | CN | disclosed |
| WO-2022255357-A1 | POLYETHER-POLYSILOXANE BLOCK COPOLYMER-CONTAINING COMPOSITION HAVING IMPROVED FOAM ENHANCING PROPERTIES, USE THEREOF AND PRODUCTION METHOD THEREOF | ダウ・東レ株式会社 | 2022-12-08 | — | — | WO | disclosed |
| CN-110891421-B | Microbicidal composition | 营养与生物科技美国第二有限公司 | 2022-09-13 | — | — | CN | disclosed |
| EP-4051239-A1 | POLOXAMER COMPOSITIONS WITH REDUCED SOL-GEL TRANSITION TEMPERATURES AND METHODS OF REDUCING THE SOL-GEL TRANSITION TEMPERATURE OF POLOXAMER COMPOSITIONS | Rochal Technologies LLC (US) | 2022-09-07 | — | — | EP | disclosed |
| CN-114929200-A | Method for lowering sol-gel transition temperature | 罗查尔科技有限责任公司 | 2022-08-19 | — | — | CN | disclosed |
| EP-0533213-A1 | Use of azelastin and glycerine ethers for the treatment of psoriasis | ASTA Medica Aktiengesellschaft (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5110814-A | Antiinflammatory agents; ulcerative colitis | ASTA PHARMA AG (DE) | 1992-05-05 | — | — | US | disclosed |
| EP-0419998-A2 | Use of alkylphosphonic acid derivatives for the treatment of psoriasis | ASTA Medica Aktiengesellschaft (DE) | 1991-04-03 | — | — | EP | disclosed |
| US-3959390-A | Process of producing mono and polyhydroxyl ethers | L'OREAL (FR) | 1976-05-25 | — | — | US | disclosed |
| US-3959185-A | Perfume blend including 2-keto-6-substituted-dioxanes-(1,4) | LEVER BROTHERS COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
| US-3952016-A | FRAGRANCE, FLAVOR | LEVER BROTHERS COMPANY (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12090205-B2 | Poloxamer compositions with reduced sol-gel transition temperatures and methods of reducing the sol-gel transition temperature of poloxamer compositions | PAOX, HPGDS, SPTSSB | USP2 706/4885HTT 2356/4885MEN1 3789/4885 |
| US-20210121575-A1 | Poloxamer Compositions With Reduced Sol-Gel Transition Temperatures and Methods of Reducing the Sol-Gel Transition Temperature of Poloxamer Compositions | PAOX, HPGDS, SPTSSB | USP2 706/4885HTT 2356/4885MEN1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.