Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063854 | 0.87 | LMNA (0.59) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5064131 | 0.87 | CCR1 (0.60) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5061693 | 0.87 | CCR1 (0.57) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5064539 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5055981 | 0.85 | LMNA (0.60) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5055612 | 0.84 | LMNA (0.56) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5059487 | 0.84 | POLB (0.57) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5064464 | 0.84 | CCR1 (0.56) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5055442 | 0.84 | CCR1 (0.54) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA | |
| SCHEMBL5059188 | 0.84 | CCR1 (0.54) | SMN1; SMN2KDM4EALDH1A1CCR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541476-B1 | Treating multiple sclerosis or encephalomyelitis in a human | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |