Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220966 | 1.00 | PTPN1 (0.48) | PTPN1HDAC8NR1H2MEN1KMT2A | |
| SCHEMBL5204183 | 0.86 | AGTR2 (0.51) | PTPN1HDAC8ACE | |
| SCHEMBL540060 | 0.86 | PTPN1 (0.64) | PTPN1HDAC8NR1H2 | |
| SCHEMBL539175 | 0.86 | PTPN1 (0.64) | PTPN1HDAC8NR1H2 | |
| SCHEMBL7229378 | 0.86 | AGTR2 (0.51) | PTPN1HDAC8ACE | |
| SCHEMBL29773931 | 0.85 | PTPN1 (0.54) | PTPN1HDAC8 | |
| SCHEMBL29502321 | 0.85 | PTPN1 (0.54) | PTPN1HDAC8 | |
| SCHEMBL546157 | 0.85 | ESR2 (0.56) | PTPN1HDAC8ACE | |
| SCHEMBL30254985 | 0.85 | PTPN1 (0.54) | PTPN1HDAC8 | |
| SCHEMBL864823 | 0.85 | PTPN1 (0.54) | PTPN1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642384-B1 | Forming intermediate to moexipril; cyclizing levodopa with formaldehyde; protecting amine, alkylating phenols, esterifying carboxylic acid and optionally deprotecting | BRANTFORD CHEMICALS INC. (CA) | 2003-11-04 | — | — | US | claimed |
| US-6642384-B1 | Forming intermediate to moexipril; cyclizing levodopa with formaldehyde; protecting amine, alkylating phenols, esterifying carboxylic acid and optionally deprotecting | BRANTFORD CHEMICALS INC. (CA) | 2003-11-04 | — | — | US | disclosed |