Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20320623 | 0.68 | KMT2A (0.53) | POLBNOTUMNPC1RAB9APTGS2 | |
| SCHEMBL17206057 | 0.68 | POLB (0.44) | POLBNOTUMNPC1RAB9APTGS2 | |
| SCHEMBL23421466 | 0.68 | CNR1 (0.40) | PTGS2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL2347651 | 0.67 | NPC1 (0.42) | POLBNOTUMNPC1RAB9APTGS2 | |
| SCHEMBL10360347 | 0.65 | KMT2A (0.54) | POLBNOTUMNPC1RAB9APTGS2 | |
| SCHEMBL19453172 | 0.65 | OXTR (0.48) | POLBNOTUMNPC1RAB9APTGS2 | |
| SCHEMBL11635129 | 0.64 | NOTUM (0.45) | POLBNOTUMNPC1RAB9APTGS2 | |
| SCHEMBL12770967 | 0.64 | POLB (0.64) | POLBNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL12770975 | 0.64 | POLB (0.65) | POLBNOTUMNPC1RAB9APTGS2 | |
| SCHEMBL10091953 | 0.64 | NOTUM (0.62) | POLBNOTUMNPC1RAB9APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605631-B1 | Controlling fungi and pests; improved activity and plant tolerability | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-12 | — | — | US | disclosed |