Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474688 | 0.89 | CDK4 (0.40) | MAPTTAAR1LMNABAZ2BCDK4 | |
| SCHEMBL6475020 | 0.84 | F12 (0.43) | MAPTLMNABAZ2BKMT2ATRPV1 | |
| SCHEMBL6481710 | 0.78 | TRPV1 (0.45) | MAPTTAAR1LMNABAZ2BGPX4 | |
| SCHEMBL6475990 | 0.77 | KCNA5 (0.47) | TAAR1KMT2ACDK4CCND1TRPV1 | |
| Hydrochloric Acid SCHEMBL6474574 | 0.77 | HTR2A (0.46) | TAAR1KDM4EPARP1 | |
| SCHEMBL6475707 | 0.73 | CDK4 (0.45) | MAPTLMNABAZ2BCDK4CCND1 | |
| SCHEMBL22319819 | 0.73 | S1PR5 (0.47) | MAPTTAAR1KMT2AGAAKDM4E | |
| SCHEMBL6475546 | 0.72 | MAPT (0.66) | MAPTTAAR1LMNABAZ2BKMT2A | |
| SCHEMBL7226453 | 0.70 | BAZ2B (0.40) | MAPTTAAR1LMNABAZ2BKMT2A | |
| SCHEMBL5373325 | 0.69 | GPX4 (0.49) | GPX4CDK4CCND1TRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583135-B2 | Treating central nervous system disorders wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity). | PHARMACIA & UPJOHN COMPANY | 2003-06-24 | — | — | US | disclosed |