Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104417 | 0.87 | MAOB (0.54) | TSHRMAOBMAOAKMT2AALDH1A1 | |
| SCHEMBL1767329 | 0.84 | TSHR (0.65) | TSHRMAOBMAOAKMT2AALDH1A1 | |
| SCHEMBL1493670 | 0.82 | KMT2A (0.60) | TSHRMAOBMAOAKMT2AALDH1A1 | |
| SCHEMBL7221312 | 0.81 | IDO1 (0.54) | TSHRMAOBMAOAALDH1A1RAB9A | |
| SCHEMBL11503161 | 0.81 | TSHR (0.67) | TSHRMAOBMAOAKMT2AALDH1A1 | |
| SCHEMBL18714233 | 0.81 | TSHR (0.57) | TSHRMAOBMAOAKMT2AALDH1A1 | |
| SCHEMBL8114222 | 0.80 | MAOB (0.51) | TSHRMAOBMAOAKMT2AALDH1A1 | |
| SCHEMBL641742 | 0.80 | TSHR (0.64) | TSHRMAOBMAOAALDH1A1MAPT | |
| SCHEMBL7861196 | 0.80 | TSHR (0.59) | TSHRMAOBMAOAKMT2AALDH1A1 | |
| SCHEMBL925746 | 0.79 | TSHR (0.54) | TSHRMAOBMAOAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552226-B1 | Rapid; low temperature; one pot synthesis; reduced catalytic quantities of such as lewis acid and tertiary amine; entiomerically pure products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-22 | — | — | US | disclosed |
| US-6359174-B1 | REACTING ALLYL REACTANT WITH ACID CHLORIDE IN PRESENCE OF LEWIS ACID CATALYST | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-03-19 | — | — | US | disclosed |