Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861196 | 0.95 | TSHR (0.59) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL28381738 | 0.90 | TSHR (0.57) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL3147589 | 0.90 | TSHR (0.57) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL11503161 | 0.90 | TSHR (0.67) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL18714233 | 0.90 | TSHR (0.57) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL3721964 | 0.90 | TSHR (0.57) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL791926 | 0.87 | TSHR (0.62) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL10456732 | 0.87 | TSHR (0.54) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL30041959 | 0.87 | TSHR (0.54) | TSHRLMNAMAOBMAOAALDH1A1 | |
| SCHEMBL925746 | 0.87 | TSHR (0.54) | TSHRLMNAMAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010763-A | Preparation method of m-aminophenol | 浙江理工大学 | 2020-12-01 | — | — | CN | claimed |
| CN-108017479-B | Method for producing aromatic compound | 东曹株式会社 | 2022-07-29 | — | — | CN | disclosed |
| CN-114618495-A | Hierarchical porous carbon-supported nitrogen-sulfur co-coordinated cobalt monoatomic catalyst and preparation method and application thereof | 中南大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114377565-A | Membranes for removal of metal species from amines | 恩特格里斯公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-112010763-A | Preparation method of m-aminophenol | 浙江理工大学 | 2020-12-01 | — | — | CN | disclosed |
| CN-112010763-A | Preparation method of m-aminophenol | 浙江理工大学 | 2020-12-01 | — | — | CN | disclosed |
| CN-110272355-A | Azobenzene derivatives and its manufacturing method | 捷恩智株式会社 | 2019-09-24 | — | — | CN | disclosed |
| WO-2011067174-A1 | ANILINE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| US-20110130438-A1 | ANILINE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | BOLIN DAVID ROBERT | 2011-06-02 | — | — | US | disclosed |
| US-7939569-B1 | Aniline analogs as glycogen synthase activators | HOFFMANN-LA ROCHE INC. (US) | 2011-05-10 | — | — | US | disclosed |
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |
| US-5565324-A | FOR IDENTIFICATION OF NON-OLIGOMERIC COMPOUND, USING SOLID SUPPORT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130438-A1 | ANILINE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | GYS2, PYGL, GYS1 | TSHR 2298/4885LMNA 454/4885MAOB 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.