SCHEMBL722301

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10268115	0.92	PDE4C (0.45)	PDE4CBRD4ALDH1A1CYP3A4TUBB4A
	SCHEMBL724951	0.92	PDE4C (0.42)	PDE4CMAPTTHRBBRD4ALDH1A1
	SCHEMBL724824	0.87	PDE4C (0.41)	PDE4CMAPTBRD4ALDH1A1CYP3A4
	SCHEMBL725258	0.85	PDE4C (0.40)	PDE4CBRD4
	SCHEMBL722753	0.84	NEK2 (0.47)	PDE4CALDH1A1CYP3A4TUBB4ATUBB
	SCHEMBL722851	0.84	PDE4C (0.46)	PDE4CTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL724038	0.83	PDE4C (0.41)	PDE4CBRD4ALDH1A1CYP3A4KDM4E
	SCHEMBL10269017	0.82	FYN (0.37)	PDE4CMAPTBRD4ALDH1A1CYP3A4
	SCHEMBL723093	0.82	PDE4C (0.55)	PDE4CBRD4ALDH1A1CYP3A4KDM4E
	SCHEMBL724404	0.81	KDM4C (0.42)	PDE4CBRD4ALDH1A1CYP3A4CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.