SCHEMBL722753

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL721518	0.90	PDE4C (0.43)	PDE4CFYNBCL9CTNNB1ALDH1A1
	SCHEMBL724404	0.89	KDM4C (0.42)	NEK2PDE4CFYNPOLBCASP6
	SCHEMBL722851	0.89	PDE4C (0.46)	PDE4CFYNJAK2JAK1TYK2
	SCHEMBL724009	0.89	PDE4C (0.41)	PDE4CFYNL3MBTL1ALDH1A1CYP3A4
	SCHEMBL10268115	0.88	PDE4C (0.45)	NEK2PDE4CALDH1A1CYP3A4TUBB4A
	SCHEMBL723070	0.88	PTPN1 (0.42)	NEK2PDE4CFYNPOLBCASP6
	SCHEMBL722431	0.86	MEN1 (0.48)	ALDH1A1CYP3A4
	SCHEMBL722839	0.86	PDE4C (0.51)	PDE4CFYNPOLBALDH1A1JAK2
	SCHEMBL723093	0.86	PDE4C (0.55)	PDE4CFYNL3MBTL1ALDH1A1CYP3A4
	SCHEMBL16638610	0.85	PDE4C (0.47)	PDE4CALDH1A1CYP3A4JAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.