Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224738 | 0.95 | THRB (0.41) | SMN1; SMN2THRBALOX15TSHRCYP2C19 | |
| SCHEMBL7218518 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2ALOX15CYP2C19ALDH1A1LMNA | |
| SCHEMBL7223109 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2THRBALOX15TSHRCYP2C19 | |
| SCHEMBL7225461 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2TDP1ALDH1A1LMNATEAD1 | |
| SCHEMBL6769239 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2THRBALOX15TSHRCYP2C19 | |
| SCHEMBL6546027 | 0.73 | POLB (0.61) | SMN1; SMN2ALOX15TDP1ALDH1A1LMNA | |
| SCHEMBL30323772 | 0.73 | POLB (0.61) | SMN1; SMN2ALOX15TDP1ALDH1A1LMNA | |
| SCHEMBL7218182 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2ALOX15CYP2C19ALDH1A1LMNA | |
| SCHEMBL27877978 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2THRBALOX15TSHRCYP2C19 | |
| SCHEMBL9058906 | 0.70 | PDK2 (0.39) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |