Dipyridyl

Dipyridyl

SCHEMBL722385

[Co].c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.93
LMNA P02545 3/20 0.93
CCR1 P32246 3/20 0.93
CCR5 P51681 3/20 0.93
CCR8 P51685 3/20 0.93
CYP1A2 P05177 1/20 0.93
POLB P06746 1/20 0.93
METAP1 P53582 1/20 0.93
BLM P54132 1/20 0.93
HIF1A Q16665 1/20 0.93
DOHH Q9BU89 1/20 0.93
P4HTM Q9NXG6 1/20 0.93
NPC1 O15118 6/20 0.74
TP53 P04637 4/20 0.74
RAB9A P51151 4/20 0.74
ALOX15 P16050 3/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
L3MBTL1 Q9Y468 3/20 0.74
HTT P42858 2/20 0.74
TDP1 Q9NUW8 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL718218 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL182275 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL5922 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL10395611 0.93 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL7909040 0.93 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL16026844 0.93 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL15136892 0.93 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115527776-A High-performance fiber solar cell and preparation method thereof 复旦大学 2022-12-27 CN claimed
US-20120269728-A1 Methods and compositions for detecting one or more target agents using tracking components ANTARA BIOSCIENCES INC. (US) 2012-10-25 US claimed
US-20090036315-A1 Device and methods for detecting and quantifying one or more target agents ANTARA BIOSCIENCES INC. (US) 2009-02-05 US claimed
CN-115527776-A High-performance fiber solar cell and preparation method thereof 复旦大学 2022-12-27 CN disclosed
US-9157884-B2 Method for electrochemically detecting target substance, method for electrochemically detecting analyte, and detection set SYSMEX CORPORATION (JP) 2015-10-13 US disclosed
US-9157885-B2 Method of electrochemically detecting target substance, method of electrochemically detecting analyte, test chip, and detection set SYSMEX CORPORATION (JP) 2015-10-13 US disclosed
EP-2515112-B1 Method for electrochemically detecting analyte SYSMEX CORP (JP) 2015-08-12 EP disclosed
US-8920626-B2 Method of electrochemically detecting a sample substance SYSMEX CORPORATION (JP) 2014-12-30 US disclosed
US-20140371082-A1 PROCESS AND APPARATUS FOR QUANTIFYING NUCLEIC ACID IN A SAMPLE BIOQUANTA SA (FR) 2014-12-18 US disclosed
US-20120267258-A1 METHOD FOR ELECTROCHEMICALLY DETECTING ANALYTE NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) 2012-10-25 US disclosed
US-20120269728-A1 Methods and compositions for detecting one or more target agents using tracking components ANTARA BIOSCIENCES INC. (US) 2012-10-25 US disclosed
EP-1837408-A1 Method of designing primers for use in method of detecting target nucleic acid and assay kit Kabushiki Kaisha Toshiba (JP) 2007-09-26 EP disclosed
US-6916614-B1 For detecting and analyzing genetic abnormalities such as DNA single base substitution SNP (single nucleotide polymorphism), plural base substitution, point mutation, and genetic loss as well as addition of base sequences in genes TUM GENE, INC. (JP) 2005-07-12 US disclosed
US-6864055-B2 Method for detecting nucleic acids FUJI PHOTO FILM CO., LTD. (JP) 2005-03-08 US disclosed
US-20040152097-A1 using solid phase synthesis for quantitative analysis with high sensitivity and enhanced throughput; genetic engineering TOPPAN PRINTING CO., LTD. (JP) 2004-08-05 US disclosed
US-20040152085-A1 Surface for collection and/or purification of nucleic acids VERIDIAN SYSTEMS DIVISION 2004-08-05 US disclosed
US-20020076717-A1 Method for detecting nucleic acids FUJI PHOTO FILM CO., LTD. (JP) 2002-06-20 US disclosed
US-20010053522-A1 DNA chip and reactive electrode FUJI PHOTO FILM CO., LTD. 2001-12-20 US disclosed
EP-1146331-A1 GENE DETECTING CHIP, DETECTOR, AND DETECTING METHOD Takenaka, Shigeori (JP) 2001-10-17 EP disclosed
US-5972692-A Gene detection method KABUSHIKI KAISHA TOSHIBA (JP) 1999-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020076717-A1 Method for detecting nucleic acids POLRMT, DNMT1, POLN KDM4E 4050/4885LMNA 440/4885CCR1 3781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.