Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898331 | 0.87 | NCF1 (0.47) | KDM4EMAPTALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL84436 | 0.85 | MAPT (0.52) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL30994907 | 0.85 | MAPT (0.52) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL19122100 | 0.81 | MAPT (0.48) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL29664507 | 0.81 | KDM4E (0.48) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL23641430 | 0.81 | MAPT (0.48) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL1253268 | 0.81 | MAPT (0.48) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL3749378 | 0.81 | MAPT (0.48) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL3747011 | 0.81 | KDM4E (0.48) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL28168712 | 0.81 | KDM4E (0.44) | KDM4EMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642255-B2 | Substituted carbocyclic or heterocyclic hydroxamic acid derivatives, e.g., (3R,4S)-N-hydroxy-1-methyl-3-(((4-((2-methyl-4 -quinolinyl)methoxylphenyl)sulfonyl)methyl)-4-piperidinecarboxamide | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-11-04 | — | — | US | disclosed |