SCHEMBL722440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15210592	0.86	PDE4C (0.45)	PDE4CFYNCHEK2BRD4JAK2
	SCHEMBL725087	0.86	FYN (0.53)	PDE4CFYNCHEK2BRD4JAK2
	SCHEMBL723093	0.85	PDE4C (0.55)	PDE4CFYNPTGESALOX5BRD4
	SCHEMBL16638610	0.84	PDE4C (0.47)	PDE4CPTGESALOX5BRD4JAK2
	SCHEMBL722937	0.83	FYN (0.48)	PDE4CFYNCHEK2PTGESALOX5
	SCHEMBL722839	0.83	PDE4C (0.51)	PDE4CFYNPTGESALOX5BRD4
	SCHEMBL721309	0.83	PDE4C (0.47)	PDE4CFYNPTGESALOX5BRD4
	SCHEMBL722753	0.82	NEK2 (0.47)	PDE4CFYNPTGESALOX5JAK2
	SCHEMBL15210488	0.81	PDE4C (0.45)	PDE4CFYNBRD4JAK2JAK1
	SCHEMBL10267299	0.81	MAPK1 (0.55)	PDE4CBRD4ALDH1A1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.