Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | TYK2 | P29597 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218250 | 0.88 | HPGD (0.44) | HPGDALDH1A1JAK2JAK1TYK2 | |
| SCHEMBL7845245 | 0.88 | POLB (0.46) | HPGDALDH1A1POLBP2RX7RAB9A | |
| SCHEMBL7217617 | 0.87 | HPGD (0.43) | HPGDALDH1A1JAK2JAK1TYK2 | |
| SCHEMBL7846596 | 0.86 | HPGD (0.45) | HPGDALDH1A1JAK2JAK1TYK2 | |
| SCHEMBL7224786 | 0.85 | HPGD (0.42) | HPGDALDH1A1JAK2JAK1TYK2 | |
| SCHEMBL7223607 | 0.85 | HPGD (0.42) | HPGDALDH1A1JAK2JAK1TYK2 | |
| SCHEMBL7218384 | 0.85 | HPGD (0.42) | HPGDALDH1A1JAK2JAK1TYK2 | |
| SCHEMBL7854326 | 0.85 | HPGD (0.57) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7854191 | 0.85 | ALDH1A1 (0.44) | HPGDALDH1A1JAK2JAK1TYK2 | |
| SCHEMBL7846577 | 0.85 | SMN1; SMN2 (0.54) | HPGDALDH1A1POLBP2RX7RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100415750-C | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2008-09-03 | — | — | CN | disclosed |
| CN-1772749-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2006-05-17 | — | — | CN | disclosed |
| CN-1239495-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2006-02-01 | — | — | CN | disclosed |
| CN-1636457-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1188419-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| CN-1188420-C | Fungicides for control of take-all disease of plants | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | disclosed |
| US-6410558-B1 | USING INDOLE OR QUINOLINE COMPOUND | MONSANTO TECHNOLOGY LLC | 2002-06-25 | — | — | US | disclosed |
| US-20010046975-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY | 2001-11-29 | — | — | US | disclosed |
| US-6252078-B1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0749416-A1 | SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1996-12-27 | — | — | EP | disclosed |
| US-5498630-A | SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |
| WO-1995024380-A1 | SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| CN-1085221-A | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1994-04-13 | — | — | CN | disclosed |
| WO-1993007751-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538231-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010046975-A1 | Fungicides for the control of take-all disease of plants | CNPY3, NAT1, CBR3 | HPGD 4230/4885ALDH1A1 3549/4885JAK2 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.