Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224489 | 0.94 | F2 (0.51) | F2HTR2AHDAC1KDM4EALDH1A1 | |
| SCHEMBL7219009 | 0.90 | F2 (0.41) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7224671 | 0.86 | NTRK1 (0.40) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7216788 | 0.86 | KDM4E (0.39) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7223072 | 0.85 | F2 (0.51) | F2HDAC1 | |
| SCHEMBL7219016 | 0.85 | CA12 (0.41) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7222891 | 0.85 | F2 (0.39) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7223673 | 0.85 | F2 (0.39) | F2HDAC1KDM4ENPC1RAB9A | |
| SCHEMBL7218890 | 0.85 | NTRK1 (0.40) | F2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL7218777 | 0.85 | F2 (0.51) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6656956-B2 | Tryptase inhibitor; antiinflamamtory agents, antiallergens | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-02 | — | — | US | disclosed |