Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.43 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.43 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.43 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134511 | 0.89 | CYP3A4 (0.44) | MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6 | |
| SCHEMBL25435255 | 0.83 | HTR2C (0.41) | MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6 | |
| SCHEMBL5988413 | 0.83 | HTR2C (0.51) | MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6 | |
| SCHEMBL5989507 | 0.83 | HTR2C (0.58) | MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6 | |
| SCHEMBL20001489 | 0.81 | MAP2K4 (0.48) | MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6 | |
| SCHEMBL12881956 | 0.80 | HTR6 (0.44) | HTR2AHTR2BHTR7HTR6GSK3B | |
| SCHEMBL1144803 | 0.80 | PDPK1 (0.54) | HTR2CHTR2AHTR2BPDPK1CYP1A2 | |
| SCHEMBL7133357 | 0.79 | HTR2A (0.43) | MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6 | |
| SCHEMBL1144988 | 0.78 | KDM4E (0.50) | MAPK1MAP2K4MAPKAPK3MAPK6HTR7 | |
| SCHEMBL6227298 | 0.78 | HTR2A (0.42) | MAPK1MAP2K4MAPKAPK2MAPKAPK3MAPK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608049-B2 | Indazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
| US-20020193610-A1 | Indazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193610-A1 | Indazoles | CYP3A43, CYP3A5, CYP3A4 | MAPK1 4226/4885MAP2K4 3882/4885MAPKAPK2 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.