Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 19/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 18/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 17/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224435 | 0.95 | ADORA2A (0.44) | ADORA3ADORA2AADORA1ADORA2B | |
| Formic Acid SCHEMBL7224826 | 0.92 | ADORA3 (0.49) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7231239 | 0.92 | ADORA3 (0.48) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5094350 | 0.91 | ADORA3 (0.52) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7452277 | 0.90 | ADORA3 (0.45) | ADORA3ADORA2AADORA1ADORA2B | |
| Formic Acid SCHEMBL7224432 | 0.87 | ADORA3 (0.49) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5093509 | 0.86 | ADORA3 (0.52) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7231584 | 0.85 | ADORA3 (0.53) | ADORA3ADORA2AADORA1ADORA2B | |
| Formic Acid SCHEMBL7231233 | 0.83 | ADORA3 (0.54) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7231864 | 0.83 | ADORA3 (0.42) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528494-B2 | Antiinflammatory agents | COX BRIAN (GB) | 2003-03-04 | — | — | US | disclosed |
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | disclosed |