Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.55 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984230 | 0.94 | TBXA2R (0.60) | TBXA2RTBXAS1SGMS1 | |
| SCHEMBL7225547 | 0.89 | TBXA2R (0.60) | TBXA2RTBXAS1 | |
| SCHEMBL7235498 | 0.85 | TBXA2R (0.59) | TBXA2RTBXAS1 | |
| SCHEMBL6186223 | 0.83 | TBXA2R (0.59) | TBXA2RTBXAS1 | |
| SCHEMBL6184164 | 0.79 | TBXA2R (0.58) | TBXA2RTBXAS1 | |
| SCHEMBL7227176 | 0.78 | TBXA2R (0.57) | TBXA2RTBXAS1 | |
| SCHEMBL6182528 | 0.78 | TBXA2R (0.57) | TBXA2RTBXAS1 | |
| Hydrochloric Acid SCHEMBL7227614 | 0.78 | TBXA2R (0.56) | TBXA2RTBXAS1 | |
| SCHEMBL8595627 | 0.77 | TBXAS1 (0.73) | TBXA2RTBXAS1 | |
| SCHEMBL14327858 | 0.76 | TBXA2R (1.00) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |