SCHEMBL722557

SCHEMBL722557

c1coc(-c2ccc(-c3ncco3)cc2)n1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.64
HPGDS O60760 1/20 0.55
CHRNA7 P36544 1/20 0.49
CHRNA10 Q9GZZ6 1/20 0.49
CHRNA9 Q9UGM1 1/20 0.49
HDAC4 P56524 1/20 0.46
KCNJ1 P48048 1/20 0.43
KCNH2 Q12809 1/20 0.43
BRD4 O60885 2/20 0.40
EDNRB P24530 1/20 0.38
EDNRA P25101 1/20 0.38
ADRB3 P13945 1/20 0.38
CCNC P24863 1/20 0.37
CDK8 P49336 1/20 0.37
GLRA3 O75311 1/20 0.37
GLRB P48167 1/20 0.37
LCK P06239 1/20 0.35
KIT P10721 1/20 0.35
FAAH O00519 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28257875 0.97 LTA4H (0.62) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL28320605 0.97 LTA4H (0.62) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL28362996 0.97 LTA4H (0.62) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL17704300 0.91 LTA4H (0.56) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL3054443 0.89 LTA4H (0.55) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL5571760 0.89 LTA4H (0.70) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL2025419 0.89 LTA4H (0.55) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL3040421 0.89 LTA4H (0.55) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL1169590 0.89 LTA4H (0.55) LTA4HHPGDSCHRNA7CHRNA10CHRNA9
SCHEMBL3031252 0.89 LTA4H (0.55) LTA4HHPGDSCHRNA7CHRNA10CHRNA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240085153-A1 Enhanced Impact Resistant Material BARANOWITZ STEVEN (US) 2024-03-14 US claimed
CN-107828373-B Modified corn stalk composite fiber reinforced friction material and preparation method thereof 吉林大学 2023-08-29 CN claimed
CN-113564937-B Polyurethane composition for capsule material, and preparation method and application thereof 中国乐凯集团有限公司 2023-07-21 CN claimed
CN-116278308-A Flexible composite material and preparation method thereof 中国乐凯集团有限公司 2023-06-23 CN claimed
CN-115232043-A Quantum dot ligand, quantum dot, QLED light-emitting device and preparation method thereof 京东方科技集团股份有限公司 2022-10-25 CN claimed
WO-2022155561-A1 ENHANCED IMPACT RESISTANT MATERIAL BARANOWITZ STEVEN (US) 2022-07-21 WO claimed
CN-114207344-A Liner collapse mitigation for class IV conformable pressure vessels 莱纳玛公司 2022-03-18 CN claimed
CN-214847796-U Spiral optical rotation electric composite cable 上海溪淇电子科技有限公司 2021-11-23 CN claimed
US-8585998-B2 Method for producing graphite film, and graphite film produced by the method KANEKA CORPORATION (JP) 2013-11-19 US claimed
US-20120052222-A1 LIGHTWEIGHT BALLISTIC PROTECTION MATERIALS, GAGNE ROBERT R (US) 2012-03-01 US claimed
EP-0696297-B1 RIGID ROD POLYMER BASED ON PYRIDOBISIMIDAZOLE AKZO NOBEL NV (NL) 1998-08-05 EP claimed
US-5766765-A Generally flat member having smooth surfaces and made of highly oriented graphite MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-06-16 US claimed
EP-0752325-A1 PNEUMATIC RADIAL TIRE THE YOKOHAMA RUBBER CO., LTD. (JP) 1997-01-08 EP claimed
US-5487941-A MOLDING LAYERS WITH FILAMENTS AND LAMINATION, HELICAL FIBER WRAPPING POLYMER BINDING PEPIN JOHN N (US) 1996-01-30 US claimed
US-5420224-A Films and fibers with benzoxazole groups THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1995-05-30 US claimed
EP-0336448-B1 ELECTROACOUSTIC DIAPHRAGM AND METHOD FOR MAKING SAME MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-01-27 EP claimed
US-5102723-A Structural sandwich panel with energy-absorbing material pierced by rigid rods PEPIN JOHN N (US) 1992-04-07 US claimed
US-5064019-A Pyrolytic graphite film with discontinuous resin layer; high strength MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-11-12 US claimed
US-5043185-A Method for fabricating a graphite film for use as an electroacoustic diaphragm MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-08-27 US claimed
EP-0336448-A2 Electroacoustic diaphragm and method for making same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-10-11 EP claimed