Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | IAPP | P10997 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174387 | 0.85 | CYP1A2 (0.41) | KDM4EL3MBTL1MAPK1IAPPMAPT | |
| SCHEMBL7107317 | 0.84 | CTSA (0.47) | KDM4EL3MBTL1MAPK1IAPPMAPT | |
| SCHEMBL7234015 | 0.83 | KDM4E (0.68) | KDM4EL3MBTL1MAPK1MAPTRAB9A | |
| SCHEMBL31691241 | 0.81 | IAPP (0.45) | KDM4EL3MBTL1MAPK1IAPPMAPT | |
| Hydrochloric Acid SCHEMBL7235077 | 0.81 | KDM4E (0.66) | KDM4EL3MBTL1MAPK1MAPTRAB9A | |
| SCHEMBL7235075 | 0.81 | KDM4E (0.47) | KDM4EL3MBTL1CYP1A2NPC1CYP3A4 | |
| SCHEMBL5708926 | 0.81 | NNMT (0.50) | KDM4EL3MBTL1MAPK1CYP1A2GAA | |
| SCHEMBL14918993 | 0.81 | KDM4E (0.71) | KDM4EL3MBTL1MAPK1MAPTCYP1A2 | |
| SCHEMBL7225724 | 0.80 | MAPT (0.51) | KDM4EL3MBTL1MAPK1MAPTCYP1A2 | |
| SCHEMBL4651223 | 0.80 | MAPK1 (0.43) | KDM4EMAPK1IAPPMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610853-B1 | N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide | KUREHA KAGAKU KOGYO K.K. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1069112-A1 | N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-01-17 | — | — | EP | disclosed |