SCHEMBL7226569

SCHEMBL7226569

O=C(CCC1CCNCC1)c1ccc2c(c1)CCN(Cc1ccccc1)CC2

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 18/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7236773 0.99 ACHE (0.83) ACHE
SCHEMBL7227301 0.94 ACHE (0.75) ACHE
Hydrochloric Acid SCHEMBL7228225 0.93 ACHE (0.74) ACHE
SCHEMBL9207777 0.92 ACHE (1.00) ACHE
SCHEMBL7846382 0.91 ACHE (0.84) ACHE
Hydrochloric Acid SCHEMBL9204650 0.91 ACHE (0.98) ACHE
SCHEMBL7226825 0.90 ACHE (0.69) ACHE
SCHEMBL7235834 0.89 ACHE (0.68) ACHE
Hydrochloric Acid SCHEMBL7235559 0.89 ACHE (0.68) ACHE
Hydrochloric Acid SCHEMBL7237077 0.88 ACHE (0.67) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed
EP-1122252-A1 NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME Takeda Chemical Industries, Ltd. (JP) 2001-08-08 EP disclosed