SCHEMBL7227178

SCHEMBL7227178

CC(=O)N1CCC(CCC(=O)c2ccc3c(c2)CNCCC3)CC1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 17/20 0.69
MCHR1 Q99705 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7236407 0.94 ACHE (0.62) ACHEMCHR1
SCHEMBL7226175 0.87 ACHE (0.67) ACHEMCHR1
Hydrochloric Acid SCHEMBL9210231 0.85 ACHE (0.68) ACHE
SCHEMBL9200187 0.84 ACHE (0.69) ACHE
SCHEMBL9202140 0.84 ACHE (0.69) ACHE
SCHEMBL7234780 0.82 ACHE (1.00) ACHE
SCHEMBL7227504 0.82 ACHE (0.70) ACHE
Hydrochloric Acid SCHEMBL9204910 0.81 ACHE (0.98) ACHE
SCHEMBL9203690 0.81 ACHE (0.69) ACHE
SCHEMBL7237446 0.81 MCHR1 (0.55) ACHEMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed