SCHEMBL7227265

SCHEMBL7227265

CC(=O)N1CCc2ccc(C(=O)CCCC3CCN(Cc4ccc(F)cc4)CC3)cc2CC1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 7/20 0.66
ACHE P22303 9/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7228197 0.91 ACHE (0.64) MCHR1ACHE
Hydrochloric Acid SCHEMBL7236778 0.90 ACHE (0.62) MCHR1ACHE
Hydrochloric Acid SCHEMBL7236495 0.89 ACHE (0.59) MCHR1ACHE
Hydrochloric Acid SCHEMBL7236442 0.88 ACHE (0.66) ACHE
SCHEMBL7233798 0.87 ACHE (0.64) MCHR1ACHE
Hydrochloric Acid SCHEMBL7227448 0.86 ACHE (0.71) MCHR1ACHE
Hydrochloric Acid SCHEMBL7227462 0.86 ACHE (0.63) MCHR1ACHE
SCHEMBL7235724 0.86 ACHE (0.56) MCHR1ACHE
Hydrochloric Acid SCHEMBL7227550 0.85 ACHE (0.59) ACHE
SCHEMBL7226386 0.85 MCHR1 (0.56) MCHR1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed