SCHEMBL724009

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL721518	0.90	PDE4C (0.43)	PDE4CFYNJAK2JAK1TYK2
	SCHEMBL724106	0.89	PDE4C (0.44)	PDE4CFYNJAK2JAK1TYK2
	SCHEMBL722753	0.89	NEK2 (0.47)	PDE4CFYNJAK2JAK1TYK2
	SCHEMBL722431	0.88	MEN1 (0.48)	ALDH1A1CYP3A4HPGDCYP2C19KDM4E
	SCHEMBL10267307	0.88	CFTR (0.46)	PDE4CFYNBRAFBRD4HPGD
	SCHEMBL724898	0.86	FYN (0.52)	FYNBRD4HPGD
	SCHEMBL723997	0.85	MAPT (0.50)	FYNALDH1A1CYP3A4HPGDCYP2C19
	SCHEMBL723093	0.83	PDE4C (0.55)	PDE4CFYNJAK2JAK1TYK2
	SCHEMBL16638610	0.82	PDE4C (0.47)	PDE4CJAK2JAK1TYK2JAK3
	SCHEMBL722941	0.82	CYP1A1 (0.40)	PDE4CFYNALDH1A1CYP3A4BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.