SCHEMBL7227752

SCHEMBL7227752

COC(=O)c1ccccc1S(=O)(=O)NC(=O)c1cc(OC)cc(OC)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA5A P35218 1/20 0.45
CA9 Q16790 1/20 0.45
MAPT P10636 1/20 0.43
SLC40A1 Q9NP59 1/20 0.43
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
KDM4E B2RXH2 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41
PTPN5 P54829 1/20 0.41
PPARG P37231 1/20 0.41
BRD4 O60885 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7236917 0.89 CA1 (0.45) KMT2AMEN1CA1CA2CA5A
SCHEMBL7226908 0.88 KMT2A (0.44) KMT2AMEN1CA1CA2CA5A
SCHEMBL7235867 0.88 KMT2A (0.49) KMT2AMEN1CA1CA2CA5A
SCHEMBL7006978 0.83 KMT2A (0.54) KMT2AMEN1CA1CA2CA5A
SCHEMBL27614193 0.82 MEN1 (0.48) KMT2AMEN1CA1CA2CA5A
SCHEMBL7235180 0.81 KMT2A (0.52) KMT2AMEN1CA1CA2CA5A
SCHEMBL7226318 0.77 CA1 (0.45) KMT2AMEN1CA1CA2CA5A
SCHEMBL1405765 0.77 GAA (0.59) KMT2AMEN1CA1CA2CA5A
SCHEMBL7235157 0.76 CA1 (0.46) KMT2AMEN1CA1CA2CA5A
SCHEMBL7227546 0.76 CTSA (0.46) KMT2AMEN1CA1CA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6610853-B1 N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide KUREHA KAGAKU KOGYO K.K. (JP) 2003-08-26 US disclosed
EP-1069112-A1 N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-01-17 EP disclosed