SCHEMBL1405765

SCHEMBL1405765

COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.77

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.59
CDK1 P06493 1/20 0.54
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
NPC1 O15118 1/20 0.49
MAPT P10636 3/20 0.48
TP53 P04637 1/20 0.48
GLA P06280 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA5A P35218 1/20 0.47
CA9 Q16790 1/20 0.47
CYP1A2 P05177 1/20 0.46
SLC40A1 Q9NP59 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10341393 0.93 GAA (0.52) GAACDK1KMT2AMEN1NPC1
SCHEMBL9419172 0.93 GAA (0.52) GAACDK1KMT2AMEN1NPC1
SCHEMBL9364617 0.92 GAA (0.59) GAACDK1KMT2AMEN1NPC1
SCHEMBL7932024 0.92 GAA (0.53) GAACDK1KMT2AMEN1NPC1
SCHEMBL9467729 0.92 GAA (0.53) GAACDK1KMT2AMEN1NPC1
SCHEMBL10645916 0.91 GAA (0.53) GAACDK1KMT2AMEN1NPC1
SCHEMBL10469643 0.91 GAA (0.59) GAACDK1KMT2AMAPTTP53
SCHEMBL10753795 0.91 GAA (0.59) GAACDK1KMT2ANPC1MAPT
SCHEMBL941471 0.90 GAA (0.49) GAACDK1KMT2AMEN1NPC1
SCHEMBL10860638 0.90 GAA (0.49) GAACDK1KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5849665-A Synergistic composition and process for selective weed control NOVARTIS CORPORATION (US) 1998-12-15 US claimed
US-5672566-A MIXTURES OF 6-ALKYL-3-ALKYL(OR HALOALKYL-)PHENYL-5-PHENYL 2,3-DIHYDRO-4H-1,3-OXAZIN-4-ONES WITH OTHER HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1997-09-30 US claimed
EP-0480871-B1 Synergistic agents and method for selective control of weeds CIBA GEIGY AG (CH) 1995-12-13 EP claimed
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
US-5108482-A Protect crep plant against phytotoxic action of herbicide; plant growth regulator CIBA-GEIGY CORPORATION (US) 1992-04-28 US claimed
EP-0224441-B1 PLANT GROWTH REGULATING AGENTS CIBA-GEIGY AG (CH) 1990-06-20 EP claimed
EP-0122231-B1 HERBICIDAL AGENT CIBA-GEIGY AG (CH) 1990-01-17 EP claimed
EP-0117014-B1 HERBICIDAL N-HYDROXY-N'-SULFONYLGUANIDINES AND SULFONAMIDE INNER SALTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-06 EP claimed
US-4484939-A PRE-AND POST-EMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-11-27 US claimed
EP-0117014-A1 Herbicidal N-hydroxy-N'-sulfonylguanidines and sulfonamide inner salts E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-08-29 EP claimed
US-4394506-A HERBICIDWS, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-19 US claimed
EP-0007687-B1 SULFONAMIDES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING SAID SULFONAMIDES AND A METHOD FOR CONTROLLING THE GROWTH OF VEGETATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-30 EP claimed
EP-0007687-A1 Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-06 EP claimed
US-9163110-B2 Granule coated with urethane resin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-20 US disclosed
US-8871681-B2 Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and certain sulfonylureas DOW AGROSCIENCES LLC (US) 2014-10-28 US disclosed
US-20140031218-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND CERTAIN SULFONYLUREAS DOW AGROSCIENCES LLC (US) 2014-01-30 US disclosed
EP-0030139-A2 Herbicidal ureas and isoureas, preparation and use thereof, and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-10 EP disclosed
EP-0030138-A1 Herbicidal sulfonamides, and compositions, preparation and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-10 EP disclosed
US-4238621-A CARBONYLBENZENESULFONYL ISOCYANATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-12-09 US disclosed
EP-0007687-A1 Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140031218-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND CERTAIN SULFONYLUREAS PFAS, PDXK, PFKFB3 GAA 4124/4885CDK1 3552/4885KMT2A 2574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.