Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CTSA | P10619 | 10/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607584 | 1.00 | MME (0.53) | MMEMMEL1PPARGPPARACTSA | |
| Hydrochloric Acid SCHEMBL6607511 | 0.99 | MME (0.52) | MMEMMEL1PPARGPPARACTSA | |
| Hydrochloric Acid SCHEMBL7229517 | 0.86 | PDE4A (0.46) | MMEMMEL1PPARGPPARACTSA | |
| SCHEMBL20546324 | 0.85 | CTSA (0.61) | CTSA | |
| SCHEMBL20546326 | 0.85 | CTSA (0.61) | CTSA | |
| SCHEMBL20545890 | 0.85 | CTSA (0.50) | CTSATNF | |
| SCHEMBL20545888 | 0.85 | CTSA (0.50) | CTSATNF | |
| SCHEMBL6784104 | 0.84 | ITGB1 (0.49) | CTSA | |
| SCHEMBL7227091 | 0.84 | ITGB1 (0.49) | CTSA | |
| SCHEMBL7235672 | 0.83 | CTSA (0.50) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645939-B1 | Very late antigen-4 (VLA) integrin antagonists; antiallergens, antiasthmatics, and antiinflammatory agents; multiple sclerosis, autoimmune disease treatment | MERCK & CO., INC. | 2003-11-11 | — | — | US | disclosed |