Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 8/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20546204 | 0.86 | CTSA (0.63) | CTSA | |
| SCHEMBL20546206 | 0.86 | CTSA (0.63) | CTSA | |
| SCHEMBL20545888 | 0.84 | CTSA (0.50) | CTSATPH1 | |
| SCHEMBL20545890 | 0.84 | CTSA (0.50) | CTSATPH1 | |
| SCHEMBL20546209 | 0.84 | CTSA (0.53) | CTSAFFAR1 | |
| SCHEMBL20546211 | 0.84 | CTSA (0.53) | CTSAFFAR1 | |
| SCHEMBL20545218 | 0.83 | CTSA (0.50) | CTSAPTGDR2 | |
| SCHEMBL20545217 | 0.83 | CTSA (0.50) | CTSAPTGDR2 | |
| SCHEMBL7227941 | 0.83 | MME (0.53) | CTSA | |
| SCHEMBL6607584 | 0.83 | MME (0.53) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645939-B1 | Very late antigen-4 (VLA) integrin antagonists; antiallergens, antiasthmatics, and antiinflammatory agents; multiple sclerosis, autoimmune disease treatment | MERCK & CO., INC. | 2003-11-11 | — | — | US | disclosed |