Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7236346 | 0.92 | HTR2B (0.31) | HTR2BSIGMAR1HTR1ATMEM97PTPN1 | |
| SCHEMBL7226253 | 0.90 | HTR2B (0.30) | HTR2BSIGMAR1HTR1ATMEM97 | |
| SCHEMBL5854236 | 0.86 | PTPN1 (0.36) | HTR2BSIGMAR1HTR1ATMEM97PTPN1 | |
| SCHEMBL7227523 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL7813221 | 0.75 | HTR2B (0.36) | HTR2BSIGMAR1HTR1ATMEM97PTPN1 | |
| SCHEMBL6939169 | 0.74 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL27560379 | 0.73 | PTPN1 (0.35) | HTR2BSIGMAR1HTR1ATMEM97PTPN1 | |
| SCHEMBL5856178 | 0.71 | HTR2B (0.38) | HTR2BSIGMAR1HTR1ATMEM97PTPN1 | |
| SCHEMBL5854163 | 0.71 | PTPN1 (0.37) | HTR2BSIGMAR1HTR1ATMEM97PTPN1 | |
| SCHEMBL7219256 | 0.71 | ROR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552068-B1 | Having anti-estrogenic activity; for use in therapy | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-1241167-A1 | 3-ETHYL-, 3-PROPYL- OR 3-BUTYL-CHROMAN AND -THIOCHROMAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |