SCHEMBL7228205

SCHEMBL7228205

O=C(CCCC1CCNCC1)c1ccc2c(c1)CN(Cc1ccccc1)CCC2

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 16/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7237141 0.94 ACHE (0.72) ACHE
Hydrochloric Acid SCHEMBL7233511 0.94 ACHE (0.71) ACHE
Hydrochloric Acid SCHEMBL7246562 0.91 ACHE (0.65) ACHE
SCHEMBL7227301 0.89 ACHE (0.75) ACHE
Hydrochloric Acid SCHEMBL7228225 0.88 ACHE (0.74) ACHE
SCHEMBL7228047 0.88 ACHE (0.49) ACHE
Hydrochloric Acid SCHEMBL7226946 0.86 ACHE (0.57) ACHE
Hydrochloric Acid SCHEMBL7237185 0.86 ACHE (0.61) ACHE
SCHEMBL7236538 0.85 ACHE (0.74) ACHE
SCHEMBL7228160 0.85 ACHE (0.65) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed