⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892008 | 0.65 | — | — | |
| SCHEMBL11473877 | 0.61 | — | — | |
| SCHEMBL423114 | 0.60 | — | — | |
| SCHEMBL4724125 | 0.60 | — | — | |
| SCHEMBL10835394 | 0.60 | — | — | |
| SCHEMBL4665338 | 0.57 | — | — | |
| SCHEMBL9128234 | 0.57 | — | — | |
| SCHEMBL2115323 | 0.52 | — | — | |
| SCHEMBL255651 | 0.44 | — | — | |
| SCHEMBL797174 | 0.34 | TTR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111206262-A | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2020-05-29 | — | — | CN | claimed |
| EP-0944591-B1 | VITAMIN D IMMUNOASSAY SYSTEMS | IMMUNODIAGNOSTIC SYSTEMS LTD (GB) | 2002-06-05 | — | — | EP | claimed |
| EP-0944591-A2 | VITAMIN D IMMUNOASSAY SYSTEMS | Immunodiagnostic Systems Limited (GB) | 1999-09-29 | — | — | EP | claimed |
| WO-1998021580-A2 | VITAMIN D IMMUNOASSAY SYSTEMS | IMMUNODIAGNOSTIC SYSTEMS LIMITED (GB) | 1998-05-22 | — | — | WO | claimed |
| CN-110683991-A | Gemini ionic liquid surfactant, synthetic method thereof and oil displacement system | 东北石油大学 | 2020-01-14 | — | — | CN | disclosed |
| US-6525074-B2 | Peptidomimetic macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras | MERCK & CO., INC. | 2003-02-25 | — | — | US | disclosed |
| US-6413964-B1 | 14-AMINO-14-(1-METHYL-1H-IMIDAZOL-5-YL)-8-OXA-2-THIA-1,18 -DIAZATETRACYCLO(16.2.2.1(3,7).1(9,13))TETRACOSA-3(24),4,6, 9(23),10,12-HEXAENE-10-CARBONITRILE 2,2-DIOXIDE, FOR EXAMPLE; USE IN RADIOTHERAPY, CHEMOTHERAPY AS SENSITIZER | MERCK & CO., INC. | 2002-07-02 | — | — | US | disclosed |
| EP-0944591-B1 | VITAMIN D IMMUNOASSAY SYSTEMS | IMMUNODIAGNOSTIC SYSTEMS LTD (GB) | 2002-06-05 | — | — | EP | disclosed |
| US-20020049217-A1 | Inhibitors of prenyl-protein transferase | MERCK SHARP & DOHME CORP. | 2002-04-25 | — | — | US | disclosed |
| WO-2001051126-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051125-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-07-19 | — | — | WO | disclosed |
| EP-0944591-A2 | VITAMIN D IMMUNOASSAY SYSTEMS | Immunodiagnostic Systems Limited (GB) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998021580-A2 | VITAMIN D IMMUNOASSAY SYSTEMS | IMMUNODIAGNOSTIC SYSTEMS LIMITED (GB) | 1998-05-22 | — | — | WO | disclosed |
| US-4814442-A | 6-hydroxyethyl-2-substituted thio-penem-3-carboxylates | SCHERING CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| US-4530793-A | Containing a thio group in position 2, carboxy group in position 3 and a hydroxyalkyl group in position 6 | SCHERING CORPORATION (US) | 1985-07-23 | — | — | US | disclosed |