SCHEMBL255651

SCHEMBL255651

Ic1ccc(I)nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14155725 0.80
Iodide SCHEMBL17396697 0.78
SCHEMBL14184747 0.74 TRPV4 (0.38)
SCHEMBL12236588 0.72 RAB9A (0.50)
SCHEMBL3298218 0.71
SCHEMBL3134692 0.66
SCHEMBL4669899 0.66
SCHEMBL198094 0.60
SCHEMBL67142 0.53
SCHEMBL10597056 0.53 HDAC8 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107986431-A A kind of polyurethane catalytic filler for electric field-enhanced oxygen-enriching device 北京中科宇清环保有限公司 2018-05-04 CN claimed
CN-107963696-A It is a kind of based on electric field-enhanced cutting fluid oxygen-enriching device 北京中科宇清环保有限公司 2018-04-27 CN claimed
EP-4724441-A1 ISOINDOLINONE AND DIHYDROPYRROLOPRIDINONE COMPOUNDS AND USES THEREOF Revir Therapeutics, Inc. (US) 2026-04-15 EP disclosed
EP-4192823-B9 DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES SANIONA AS (DK) 2026-03-18 EP disclosed
US-12559486-B2 Tau-protein targeting compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 US disclosed
US-20260001863-A1 NOVEL PYRIDAZINES BOEHRINGER INGELHEIM INT (DE) 2026-01-01 US disclosed
EP-4192823-B1 DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES SANIONA AS (DK) 2025-12-17 EP disclosed
EP-4624463-A1 SPIRO DERIVATIVE AS KIF18A INHIBITOR Insilico Medicine IP Limited (HK) 2025-10-01 EP disclosed
US-12391667-B2 N-methyl, n-(6-(methoxy)pyridazin-3-yl) amine derivatives as Autotaxin (ATX) modulators for the treatment of inflammatory airway or fibrotic diseases BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-08-19 US disclosed
US-20250250253-A1 SALT FORMS AND POLYMORPHS OF (R)-1-(4-(6-(2-(4-(3,3-DIFLUOROCYCLOBUTOXY)-6-METHYLPYRIDIN-2-YL)ACETAMIDO) PYRIDAZIN-3-YL)-2-FLUOROBUTYL)-N-METHYL-1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-08-07 US disclosed
EP-4596558-A2 DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES Boehringer Ingelheim International GmbH (DE) 2025-08-06 EP disclosed
US-4992433-A Viricides JANSSEN PHARMACEUTICA N.V. (BE) 1991-02-12 US disclosed
EP-0320032-A1 Pyridizinamine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1989-06-14 EP disclosed
CN-1033274-A The preparation method of new Pyridazinyl amine derivative JANSSEN PHARMACEUTICA NV (BE) 1989-06-07 CN disclosed
EP-0156433-A2 Anti-virally active pyridazinamines JANSSEN PHARMACEUTICA N.V. (BE) 1985-10-02 EP disclosed
US-4145423-A TREATMENT OF SCHISTOSOMIASIS AND AMOEBIASIS, NEMATODES, ANTIPROTAZOA RHONE-POULENC INDUSTRIES (FR) 1979-03-20 US disclosed
US-4144339-A TREATMENT OF BILHARZIASIS RHONE-POULENC INDUSTRIES (FR) 1979-03-13 US disclosed
US-4138487-A NEMATOCIDES RHONE-POULENC INDUSTRIES (FR) 1979-02-06 US disclosed
US-4110450-A BILHARZIASIS RHONE-POULENC INDUSTRIES (FR) 1978-08-29 US disclosed
US-4104386-A Derivatives of 1,2-dithiole and anti-bilharzia compositions thereof RHONE-POULENC INDUSTRIES (FR) 1978-08-01 US disclosed