Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7236937 | 0.88 | MAOA (0.64) | MAOAADORA3SLC22A2SLC22A1ALDH1A1 | |
| SCHEMBL7333754 | 0.87 | MAOA (1.00) | MAOAADORA3SLC22A2SLC22A1ALDH1A1 | |
| SCHEMBL7228422 | 0.86 | MAOA (0.62) | MAOAADORA3SLC22A2SLC22A1ALDH1A1 | |
| SCHEMBL12071050 | 0.85 | MAOA (0.79) | MAOAADORA3SLC22A2SLC22A1ALDH1A1 | |
| SCHEMBL8484364 | 0.82 | MAOA (1.00) | MAOAADORA3SLC22A2SLC22A1ALDH1A1 | |
| SCHEMBL7227675 | 0.79 | MAOA (0.78) | MAOAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7236943 | 0.79 | MAOA (0.78) | MAOAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7236938 | 0.79 | MAOA (0.62) | MAOAADORA3SLC22A2SLC22A1ALDH1A1 | |
| SCHEMBL31059963 | 0.77 | MAOA (0.68) | MAOAADORA3SLC22A2SLC22A1ALDH1A1 | |
| SCHEMBL31059964 | 0.77 | MAOA (0.68) | MAOAADORA3SLC22A2SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559177-B2 | For therapy or inhibiting osteoporosis or inhibiting bone demineralization, inflammatory bowel disease, Crohn's disease, ulcerative proctitis, or colitis in mammal | WYETH | 2003-05-06 | — | — | US | disclosed |
| US-20020183310-A1 | 5,11-dioxa-benzo[b]fluoren-10-one and 5-oxa-11-thia-benzo[b]fluoren-10-ones as estrogenic agents | WYETH | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183310-A1 | 5,11-dioxa-benzo[b]fluoren-10-one and 5-oxa-11-thia-benzo[b]fluoren-10-ones as estrogenic agents | ESR1, GPER1, ESR2 | MAOA 716/4885ADORA3 408/4885SLC22A2 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.