Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA4 | P22748 | 5/20 | 0.45 |
| ▸ | CA6 | P23280 | 5/20 | 0.45 |
| ▸ | CA5A | P35218 | 5/20 | 0.45 |
| ▸ | CA7 | P43166 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.45 |
| ▸ | CA3 | P07451 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250677 | 0.85 | TSHR (0.61) | TSHRSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL18782372 | 0.79 | ALDH1A1 (0.64) | TSHRSMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL6250573 | 0.78 | TSHR (0.46) | TSHRSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL11165084 | 0.75 | ALDH1A1 (0.70) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL8555147 | 0.74 | ALDH1A1 (0.50) | TSHRSMN1; SMN2ALDH1A1POLBTDP1 | |
| SCHEMBL31448243 | 0.74 | ALDH1A1 (0.50) | TSHRSMN1; SMN2ALDH1A1POLBTDP1 | |
| SCHEMBL4132618 | 0.73 | ALDH1A1 (0.64) | TSHRSMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL24515880 | 0.72 | TDP1 (0.62) | TSHRALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL1974587 | 0.72 | ALDH1A1 (0.55) | TSHRSMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL24984267 | 0.71 | ALDH1A1 (0.54) | TSHRSMN1; SMN2ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552048-B2 | For use in therapy of hyperlipidemia and arteriosclerotic disorders | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-04-22 | — | — | US | disclosed |
| US-20020072520-A1 | Sulfonylcarboxamide derivatives, process for their preparation and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2002-06-13 | — | — | US | disclosed |
| US-6342512-B1 | ANTILIPEMIC AGENTS, ATHERIOSCLEROSIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072520-A1 | Sulfonylcarboxamide derivatives, process for their preparation and their use as pharmaceuticals | LIPA, CES1, SLC5A1 | TSHR 1486/4885SMN1; SMN2 2022/4885CA12 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.