Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229875 | 0.81 | NOS2 (0.39) | NOS2 | |
| SCHEMBL1220359 | 0.74 | — | — | |
| SCHEMBL477203 | 0.72 | — | — | |
| SCHEMBL4534726 | 0.72 | SLC6A2 (0.30) | — | |
| SCHEMBL477223 | 0.66 | — | — | |
| SCHEMBL1218570 | 0.65 | POLB (0.30) | — | |
| SCHEMBL26631958 | 0.65 | CA1 (0.32) | NOS2 | |
| SCHEMBL1218550 | 0.64 | — | — | |
| SCHEMBL1219999 | 0.62 | — | — | |
| SCHEMBL1219871 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602876-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2003-08-05 | — | — | US | claimed |